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By Frank J. Dixon and Henry G. Kunkel (Eds.)

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Extra info for Advances in Immunology, Vol. 24

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However, no information is as yet available indicating that fluid-phase P is formed as a result of the activation of the properdin system. VI. Molecular Consequences of Activation of the Properdin System The action of the alternative pathway convertases on C3 and C5 is indistinguishabIe from that of their classical counterparts. The anaphyla- 18 0. GOTZE AND H. J . MULLER-EBERHARD toxin C3a has the same NH,- and COOH-terminal amino acid residues and the same biological activities regardless of whether it arose through the classical (31) or the alternative pathway (102, 103).

And Dixon, F. J. (1974). Kidney Int. 6, 157. 249. , and Schmidt, G. ( 1964). Erperientiu 20,207. 250. , and Dieminger, L. (1976). J. Immunol. 116, 1753. 251. , and Schmidt, G. (1974). Hoppe-Seyler's Z. Physiol. Chem. 355, 171. 252. , and Dieminger, L. (1976). J. Immurwl. 116, 1753. 253. , and Lynen, R. (1975). , Exp. Klin. Immunol. 149, 440. 254. , and Dieminger, L. (1975). J. Tmmund. 114, 671. 255. Volanakis, J. , Schultz, D. , and Stroud, R. M. (1976). Int. Arch. Allergy Appl. lrnmunol. 50, 68.

J. C h . Invest. 52, 1601. 50. Day, N. , and Good, R. A. 1973). 1. Clin. Invest. 52. 1698. 51. , Eisele; J. , and Lepow, I. H. (1967). J. Exp. Med. 126, 1027. 52. Dierich, M. , and Bitter-Suemann, D. ( 1974). Immunochemisty 11,527. 53. Dungern, E. von (1900). Miinch. Med. Wocbnschr. 47, 677. 54. , and Mayer, M. M. (1973). J . Immunol. 110, 1452. 55. , and Frank, M. M. (1971). J. Exp. Med. 134, 162. 56. Evans, D. , Williams, D. , Peters, D. , Sissons, J. G. , Boulton-Jones, J. , Ogg, C. , Cameron, J.

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